original idiotype - translation to russian
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original idiotype - translation to russian

Immunoglobulin idiotypes; Immunoglobulin idiotype

original idiotype      

общая лексика

генетически детерминированный идиотип

набор природных идиотипических детерминант

idiotype         

общая лексика

идиотип (набор идиотипических детерминант в молекуле антитела)

Смотрите также

original idiotype; self idiotype

original series         
первая серия

Definition

idiotype
['?d??(?)t??p]
¦ noun
1. Biology the set of genetic determinants of an individual.
2. Physiology a set of antigen-binding sites which characterizes the antibodies produced by a clone of cells.

Wikipedia

Idiotype

In immunology, an idiotype is a shared characteristic between a group of immunoglobulin or T-cell receptor (TCR) molecules based upon the antigen binding specificity and therefore structure of their variable region. The variable region of antigen receptors of T cells (TCRs) and B cells (immunoglobulins) contain complementarity-determining regions (CDRs) with unique amino acid sequences. They define the surface and properties of the variable region, determining the antigen specificity and therefore the idiotope of the molecule. Immunoglobulins or TCRs with a shared idiotope are the same idiotype. Antibody idiotype is determined by:

  • Gene rearrangement
  • Junctional diversity
  • P-nucleotides (palindromic nucleotides at sites of single-strand breaks)
  • N-nucleotides
  • Somatic hypermutations
What is the Russian for original idiotype? Translation of &#39original idiotype&#39 to Russian